Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dual specificity tyrosine-phosphorylation-regulated kinase 1A' and Ligand = 'BDBM459196'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM459196 (US10759799, Compound 64) Show SMILES O=C1NC2CCC(CC2)NCc2cncc(c2)-c2ccc3[nH]nc(-c4nc5c1cccc5[nH]4)c3c2 |(.21,1.74,;.98,3.07,;.12,4.41,;-1.34,5.18,;-2.83,5.57,;-3.61,4.25,;-4.95,3.5,;-3.47,3.1,;-2.69,4.43,;-5.35,2.01,;-4.11,1.24,;-4.16,-.18,;-5.49,-.95,;-5.49,-2.49,;-4.16,-3.26,;-2.82,-2.49,;-2.82,-.95,;-1.49,-3.26,;-1.49,-4.8,;-.15,-5.57,;1.18,-4.8,;2.64,-5.28,;3.55,-4.03,;2.64,-2.79,;3.04,-1.3,;2.07,-.1,;2.91,1.19,;2.51,2.67,;3.6,3.76,;5.09,3.36,;5.49,1.88,;4.4,.79,;4.48,-.75,;1.18,-3.26,;-.15,-2.49,)| Show InChI InChI=1S/C27H25N7O/c35-27-20-2-1-3-23-24(20)32-26(31-23)25-21-11-16(4-9-22(21)33-34-25)17-10-15(12-28-14-17)13-29-18-5-7-19(30-27)8-6-18/h1-4,9-12,14,18-19,29H,5-8,13H2,(H,30,35)(H,31,32)(H,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	448	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The DYRK1A kinase assay was run using the Ser/Thr 18 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Divis...				US Patent US10759799 (2020) BindingDB Entry DOI: 10.7270/Q2B27ZB4
					More data for this Ligand-Target Pair