Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dual specificity tyrosine-phosphorylation-regulated kinase 1A' and Ligand = 'BDBM459198'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM459198 (US10759799, Compound 97) Show SMILES O=C1CCc2cccc(c2)-c2cncc(NC(=O)c3n[nH]c4ccc(cc34)-c3cncc(CN1)c3)c2 Show InChI InChI=1S/C28H22N6O2/c35-26-7-4-17-2-1-3-19(8-17)22-10-23(16-30-15-22)32-28(36)27-24-11-20(5-6-25(24)33-34-27)21-9-18(13-31-26)12-29-14-21/h1-3,5-6,8-12,14-16H,4,7,13H2,(H,31,35)(H,32,36)(H,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	9	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The DYRK1A kinase assay was run using the Ser/Thr 18 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Divis...				US Patent US10759799 (2020) BindingDB Entry DOI: 10.7270/Q2B27ZB4
					More data for this Ligand-Target Pair