Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Dual specificity tyrosine-phosphorylation-regulated kinase 1A' and Ligand = 'BDBM484676'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM484676 (US10934297, Compound 69 | US11713320, Compound 69) Show SMILES Cn1cc(cn1)-c1cc2c(n[nH]c2cc1F)C(=O)Nc1ccc(CN2CCCC2)cc1 Show InChI InChI=1S/C23H23FN6O/c1-29-14-16(12-25-29)18-10-19-21(11-20(18)24)27-28-22(19)23(31)26-17-6-4-15(5-7-17)13-30-8-2-3-9-30/h4-7,10-12,14H,2-3,8-9,13H2,1H3,(H,26,31)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q20P144B
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM484676 (US10934297, Compound 69 | US11713320, Compound 69) Show SMILES Cn1cc(cn1)-c1cc2c(n[nH]c2cc1F)C(=O)Nc1ccc(CN2CCCC2)cc1 Show InChI InChI=1S/C23H23FN6O/c1-29-14-16(12-25-29)18-10-19-21(11-20(18)24)27-28-22(19)23(31)26-17-6-4-15(5-7-17)13-30-8-2-3-9-30/h4-7,10-12,14H,2-3,8-9,13H2,1H3,(H,26,31)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description DYRK1A: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 11-point dose-response...				US Patent US10934297 (2021) BindingDB Entry DOI: 10.7270/Q23N26GM
					More data for this Ligand-Target Pair