Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Dual specificity tyrosine-phosphorylation-regulated kinase 1A' and Ligand = 'BDBM484694'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM484694 (US10934297, Compound 87 | US11713320, Compound 87) Show SMILES FC(F)Oc1ccc(NC(=O)c2n[nH]c3ccc(cc23)-c2cnn(c2)C2CCNCC2)cn1 Show InChI InChI=1S/C22H21F2N7O2/c23-22(24)33-19-4-2-15(11-26-19)28-21(32)20-17-9-13(1-3-18(17)29-30-20)14-10-27-31(12-14)16-5-7-25-8-6-16/h1-4,9-12,16,22,25H,5-8H2,(H,28,32)(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	n/a	n/a	8	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q20P144B
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM484694 (US10934297, Compound 87 | US11713320, Compound 87) Show SMILES FC(F)Oc1ccc(NC(=O)c2n[nH]c3ccc(cc23)-c2cnn(c2)C2CCNCC2)cn1 Show InChI InChI=1S/C22H21F2N7O2/c23-22(24)33-19-4-2-15(11-26-19)28-21(32)20-17-9-13(1-3-18(17)29-30-20)14-10-27-31(12-14)16-5-7-25-8-6-16/h1-4,9-12,16,22,25H,5-8H2,(H,28,32)(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	8	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description DYRK1A: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 11-point dose-response...				US Patent US10934297 (2021) BindingDB Entry DOI: 10.7270/Q23N26GM
					More data for this Ligand-Target Pair