BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Dual specificity tyrosine-phosphorylation-regulated kinase 1A' and Ligand = 'BDBM50395381'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50395381 (CHEMBL2164716 \| US9168247, JR95) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Namur (FUNDP) Curated by ChEMBL					Assay Description Inhibition of DYRK1A kinase using RBER-CHKtide substrate by radiometric protein kinase assay				J Med Chem 55: 6489-501 (2012) Article DOI: 10.1021/jm300542e BindingDB Entry DOI: 10.7270/Q2GM88FB
University of Namur (FUNDP) Curated by ChEMBL					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50395381 (CHEMBL2164716 \| US9168247, JR95) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.12E+4	n/a	n/a	n/a	n/a	7.5	n/a
FACULTES UNIVERSITAIRES NOTRE DAME DE LA PAIX; UNIVERSITE LIBRE BRUXELLES US Patent					Assay Description A radiometric protein kinase assay (33PanQinase Activity Assay) was used for measuring the kinase activity of DYRK1A protein kinase. All kinase assay...				US Patent US9168247 (2015) BindingDB Entry DOI: 10.7270/Q2X63KQN
					More data for this Ligand-Target Pair