Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dual specificity tyrosine-phosphorylation-regulated kinase 1B' and Ligand = 'BDBM401539'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity tyrosine-phosphorylation-regulated kinase 1B (Homo sapiens (Human))	BDBM401539 (US10005769, No. 3) Show SMILES CS(=O)(=O)c1ccc2[nH]c(NC(=O)c3csc(n3)-c3ccc4OCCc4c3)nc2c1 Show InChI InChI=1S/C20H16N4O4S2/c1-30(26,27)13-3-4-14-15(9-13)23-20(22-14)24-18(25)16-10-29-19(21-16)12-2-5-17-11(8-12)6-7-28-17/h2-5,8-10H,6-7H2,1H3,(H2,22,23,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.49	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The substrate DYRKtide (synthetic peptide RRRFRPASPLRGPPK) was dissolved in freshly prepared Base Reaction Buffer (20 mM Hepes (pH 7.5), 10 mM MgCl2,...				Bioorg Med Chem Lett 19: 908-11 (2009) BindingDB Entry DOI: 10.7270/Q2F19224
					More data for this Ligand-Target Pair