Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dual specificity tyrosine-phosphorylation-regulated kinase 1B (Homo sapiens (Human)) | BDBM50434364 (CHEMBL2386764 | US9446044, 65) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Dart Neuroscience LLC Curated by ChEMBL | Assay Description Inhibition of recombinant DYRK1B (unknown origin) after 120 mins in presence of [33P]-ATP | ACS Med Chem Lett 4: 502-3 (2013) Article DOI: 10.1021/ml400137s BindingDB Entry DOI: 10.7270/Q2NK3GDP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity tyrosine-phosphorylation-regulated kinase 1B (Homo sapiens (Human)) | BDBM50434364 (CHEMBL2386764 | US9446044, 65) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113949 BindingDB Entry DOI: 10.7270/Q2M90DP7 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity tyrosine-phosphorylation-regulated kinase 1B (Homo sapiens (Human)) | BDBM50434364 (CHEMBL2386764 | US9446044, 65) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human DYRK1B using [33P]-ATP incubated for 120 mins | Citation and Details BindingDB Entry DOI: 10.7270/Q2GH9NMG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity tyrosine-phosphorylation-regulated kinase 1B (Homo sapiens (Human)) | BDBM50434364 (CHEMBL2386764 | US9446044, 65) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.83 | n/a | n/a | n/a | n/a | 7.5 | 25 |
DIAXONHIT US Patent | Assay Description The DYRK1A and DYRK1B kinase assays to determine IC50 values were performed by Reaction Biology Corporation using HotSpot technology Worldwide websit... | US Patent US9446044 (2016) BindingDB Entry DOI: 10.7270/Q2610Z7J | |||||||||||
More data for this Ligand-Target Pair |