Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dynamin-1' and Ligand = 'BDBM50268872'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dynamin-1 (Homo sapiens (Human))	BDBM50268872 (2-Cyano-N-octyl-3-[1-(2-dimethylaminoethyl)-2-meth...) Show SMILES CCCCCCCCNC(=O)C(=C\c1c(C)n(CCN(C)C)c2ccccc12)\C#N Show InChI InChI=1S/C25H36N4O/c1-5-6-7-8-9-12-15-27-25(30)21(19-26)18-23-20(2)29(17-16-28(3)4)24-14-11-10-13-22(23)24/h10-11,13-14,18H,5-9,12,15-17H2,1-4H3,(H,27,30)/b21-18+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.32E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibition of dynamin 1-mediated endocytosis internalization of Tf-A594 in human U2OS cells pretreated for 30 mins				J Med Chem 52: 3762-73 (2009) Article DOI: 10.1021/jm900036m BindingDB Entry DOI: 10.7270/Q28W3D79
					More data for this Ligand-Target Pair