Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase Mdm2' and Ligand = 'BDBM50020723'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM50020723 (CHEMBL3291437) Show SMILES Cc1[nH]c(c(c1-c1ccc(C#N)c(=O)[nH]1)-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C23H17N3O/c1-15-20(19-13-12-18(14-24)23(27)26-19)21(16-8-4-2-5-9-16)22(25-15)17-10-6-3-7-11-17/h2-13,25H,1H3,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Inhibition of GST-tagged HDM2 (unknown origin) expressed in Escherichia coli BL21 cells assessed as p53 activation by measuring inhibition of His-p53...				Eur J Med Chem 82: 472-9 (2014) Article DOI: 10.1016/j.ejmech.2014.05.082 BindingDB Entry DOI: 10.7270/Q2GT5PR8
					More data for this Ligand-Target Pair