Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase Mdm2' and Ligand = 'BDBM50300117'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM50300117 ((2'R,3S,4'R,5'R)-6-chloro-4'-(3-chlorophenyl)-N-((...) Show SMILES CC(C)(C)C[C@H]1N[C@H]([C@H](c2cccc(Cl)c2)[C@@]11C(=O)Nc2cc(Cl)ccc12)C(=O)NCC[C@H](O)CO |r| Show InChI InChI=1S/C27H33Cl2N3O4/c1-26(2,3)13-21-27(19-8-7-17(29)12-20(19)31-25(27)36)22(15-5-4-6-16(28)11-15)23(32-21)24(35)30-10-9-18(34)14-33/h4-8,11-12,18,21-23,32-34H,9-10,13-14H2,1-3H3,(H,30,35)(H,31,36)/t18-,21+,22-,23+,27-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Inhibition of his-tagged human recombinant MDM2 binding to p53-based peptide PMDM6-F by fluorescence polarization assay				J Med Chem 52: 7970-3 (2009) Article DOI: 10.1021/jm901400z BindingDB Entry DOI: 10.7270/Q2N29X17
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM50300117 ((2'R,3S,4'R,5'R)-6-chloro-4'-(3-chlorophenyl)-N-((...) Show SMILES CC(C)(C)C[C@H]1N[C@H]([C@H](c2cccc(Cl)c2)[C@@]11C(=O)Nc2cc(Cl)ccc12)C(=O)NCC[C@H](O)CO |r| Show InChI InChI=1S/C27H33Cl2N3O4/c1-26(2,3)13-21-27(19-8-7-17(29)12-20(19)31-25(27)36)22(15-5-4-6-16(28)11-15)23(32-21)24(35)30-10-9-18(34)14-33/h4-8,11-12,18,21-23,32-34H,9-10,13-14H2,1-3H3,(H,30,35)(H,31,36)/t18-,21+,22-,23+,27-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Inhibition of his-tagged human recombinant MDM2 binding to p53-based peptide PMDM6-F by fluorescence polarization assay				J Med Chem 52: 7970-3 (2009) Article DOI: 10.1021/jm901400z BindingDB Entry DOI: 10.7270/Q2N29X17
					More data for this Ligand-Target Pair