Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase Mdm2' and Ligand = 'BDBM50442799'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM50442799 (CHEMBL2443386) Show SMILES Clc1cccc(c1)-n1c2nc(=O)[nH]c(=O)c2cc2cccc(Cl)c12 Show InChI InChI=1S/C17H9Cl2N3O2/c18-10-4-2-5-11(8-10)22-14-9(3-1-6-13(14)19)7-12-15(22)20-17(24)21-16(12)23/h1-8H,(H,21,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Nottingham Curated by ChEMBL					Assay Description Inhibition of GST-tagged HDM2 (unknown origin) assessed as p53 ubiquitination by Western blot analysis				Bioorg Med Chem 21: 6868-77 (2013) Article DOI: 10.1016/j.bmc.2013.09.038 BindingDB Entry DOI: 10.7270/Q2KS6T01
					More data for this Ligand-Target Pair