Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Endothelial PAS domain-containing protein 1' and Ligand = 'BDBM373006'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial PAS domain-containing protein 1 (Homo sapiens (Human))	BDBM373006 (US10597366, Compound 161 | US9896418, Compound 161) Show SMILES CS(=O)(=O)c1ccc(Oc2cc(F)cc(F)c2)c2CC(F)(F)[C@@H](O)c12 |r| Show InChI InChI=1S/C16H12F4O4S/c1-25(22,23)13-3-2-12(11-7-16(19,20)15(21)14(11)13)24-10-5-8(17)4-9(18)6-10/h2-6,15,21H,7H2,1H3/t15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
Peloton Therapeutics, Inc. US Patent					Assay Description HIF-2a: The total assay volume was about 100 uL in the following configuration: 2 uL compound in 100% DMSO, 88 uL buffer with protein and probe and 1...				US Patent US10597366 (2020) BindingDB Entry DOI: 10.7270/Q2M32ZSW
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