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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Endothelial PAS domain-containing protein 1' and Ligand = 'BDBM50340949'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Endothelial PAS domain-containing protein 1


(Homo sapiens (Human))		BDBM50340949
PNG
((1R,2S)-1-((1R,4aS,11aR)-1-acetoxy-7-methyl-11-met...)
Show SMILES [#6]\[#6](-[#6])=[#6]\[#6@H](-[#8]-[#6](-[#6])=O)-[#6@H](-[#8]-[#6](-[#6])=O)-[#6]-1=[#6]-[#8]-[#6@H](-[#8]-[#6](-[#6])=O)-[#6@@H]-2-[#6@@H]-1-[#6]-[#6]\[#6](-[#6])=[#6]/[#6]-[#6]-[#6]-2=[#6] |r,c:28,t:14|
Show InChI InChI=1S/C26H36O7/c1-15(2)13-23(31-18(5)27)25(32-19(6)28)22-14-30-26(33-20(7)29)24-17(4)10-8-9-16(3)11-12-21(22)24/h9,13-14,21,23-26H,4,8,10-12H2,1-3,5-7H3/b16-9-/t21-,23+,24+,25-,26-/m1/s1
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Similars
Article
PubMed
n/an/an/an/a 3.40E+3n/an/an/an/a



NCI-Frederick

Curated by ChEMBL


Assay Description
Inhibition of HIF-2alpha activity in human 786-O cells by luciferase assay

Bioorg Med Chem Lett 21: 2113-5 (2011)


Article DOI: 10.1016/j.bmcl.2011.01.127
BindingDB Entry DOI: 10.7270/Q27D2VFV
More data for this
Ligand-Target Pair