Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Endothelial lipase' and Ligand = 'BDBM142060'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM142060 (US8933024, 4) Show SMILES COc1cc(cc(CO)c1OC)C(C)NC(=O)n1sc2ncccc2c1=O Show InChI InChI=1S/C18H19N3O5S/c1-10(11-7-12(9-22)15(26-3)14(8-11)25-2)20-18(24)21-17(23)13-5-4-6-19-16(13)27-21/h4-8,10,22H,9H2,1-3H3,(H,20,24)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description For characterization of the enzymatic activity of endothelial lipase and the effect of inhibitors, the phospholipase-specific substrate 1,2-bis(4,4-d...				US Patent US8933024 (2015) BindingDB Entry DOI: 10.7270/Q228069H
					More data for this Ligand-Target Pair