Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Endothelial lipase' and Ligand = 'BDBM151259'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM151259 (BDBM151425 | US8987314, B55) Show SMILES CC(=O)Nc1ccc(cc1)-c1ccc2nc(sc2c1)C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CCC(F)(F)F Show InChI InChI=1S/C22H23F3N4O6S3/c1-13(30)28-16-5-2-14(3-6-16)15-4-7-17-18(12-15)36-21(29-17)19(20(31)27-9-11-38(26,34)35)37(32,33)10-8-22(23,24)25/h2-7,12,19H,8-11H2,1H3,(H,27,31)(H,28,30)(H2,26,34,35)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	8.0	25
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US8987314 (2015) BindingDB Entry DOI: 10.7270/Q2W094N8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM151259 (BDBM151425 | US8987314, B55) Show SMILES CC(=O)Nc1ccc(cc1)-c1ccc2nc(sc2c1)C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CCC(F)(F)F Show InChI InChI=1S/C22H23F3N4O6S3/c1-13(30)28-16-5-2-14(3-6-16)15-4-7-17-18(12-15)36-21(29-17)19(20(31)27-9-11-38(26,34)35)37(32,33)10-8-22(23,24)25/h2-7,12,19H,8-11H2,1H3,(H,27,31)(H,28,30)(H2,26,34,35)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	8.0	25
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US8987314 (2015) BindingDB Entry DOI: 10.7270/Q2W094N8
					More data for this Ligand-Target Pair