Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Endothelial lipase' and Ligand = 'BDBM151499'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM151499 (US8987314, B310) Show SMILES NS(=O)(=O)CCNC(=O)C(c1nc2cc(ccc2s1)-c1ccc(F)nc1)S(=O)(=O)Cc1ccc(F)cc1 Show InChI InChI=1S/C23H20F2N4O5S3/c24-17-5-1-14(2-6-17)13-36(31,32)21(22(30)27-9-10-37(26,33)34)23-29-18-11-15(3-7-19(18)35-23)16-4-8-20(25)28-12-16/h1-8,11-12,21H,9-10,13H2,(H,27,30)(H2,26,33,34)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	8.0	25
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US8987314 (2015) BindingDB Entry DOI: 10.7270/Q2W094N8
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