Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Endothelial lipase' and Ligand = 'BDBM151534'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM151534 (US8987314, B345) Show SMILES CC(C)(O)CNC(=O)c1cccc(c1)-c1ccc2nc(sc2c1)C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CCC(F)(F)F Show InChI InChI=1S/C25H29F3N4O7S3/c1-24(2,35)14-31-21(33)17-5-3-4-15(12-17)16-6-7-18-19(13-16)40-23(32-18)20(22(34)30-9-11-42(29,38)39)41(36,37)10-8-25(26,27)28/h3-7,12-13,20,35H,8-11,14H2,1-2H3,(H,30,34)(H,31,33)(H2,29,38,39)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	8.0	25
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US8987314 (2015) BindingDB Entry DOI: 10.7270/Q2W094N8
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