Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Endothelial lipase' and Ligand = 'BDBM152295'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM152295 (US8993557, 37) Show SMILES Oc1c(ccn(CCC(F)(F)F)c1=O)C(=O)N[C@H]1CC[C@H](CC1)c1ccccc1 |r,wU:17.17,20.24,(2.67,1.44,;2.67,-.1,;1.33,-.87,;1.33,-2.41,;2.67,-3.18,;4,-2.41,;5.33,-3.18,;6.67,-2.41,;8,-3.18,;7.23,-4.52,;9.34,-3.95,;8.77,-1.85,;4,-.87,;5.33,-.1,;,-.1,;,1.44,;-1.33,-.87,;-2.67,-.1,;-4,-.87,;-5.33,-.1,;-5.33,1.44,;-4,2.21,;-2.67,1.44,;-6.67,2.21,;-6.67,3.75,;-8,4.52,;-9.34,3.75,;-9.34,2.21,;-8,1.44,)| Show InChI InChI=1S/C21H23F3N2O3/c22-21(23,24)11-13-26-12-10-17(18(27)20(26)29)19(28)25-16-8-6-15(7-9-16)14-4-2-1-3-5-14/h1-5,10,12,15-16,27H,6-9,11,13H2,(H,25,28)/t15-,16+	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	352	n/a	n/a	n/a	n/a	8.0	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase activity was measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artificial vesicle containing DMPG (Av...				US Patent US8993557 (2015) BindingDB Entry DOI: 10.7270/Q2KH0M1Z
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