Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Endothelial lipase' and Ligand = 'BDBM181696'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM181696 (US9139578, 15) Show SMILES CC(C)NC(=O)NC(c1nnc(CNS(N)(=O)=O)o1)c1nc2ccc(cc2s1)-c1ccccc1 Show InChI InChI=1S/C21H23N7O4S2/c1-12(2)24-21(29)26-18(19-28-27-17(32-19)11-23-34(22,30)31)20-25-15-9-8-14(10-16(15)33-20)13-6-4-3-5-7-13/h3-10,12,18,23H,11H2,1-2H3,(H2,22,30,31)(H2,24,26,29)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	8.0	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase activity was measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artificial vesicle containing DMPG (Av...				US Patent US9139578 (2015) BindingDB Entry DOI: 10.7270/Q2FF3R45
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