Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Endothelial lipase' and Ligand = 'BDBM187291'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM187291 (US9169240, 31 | US9169240, 38 | US9169240, 40) Show SMILES CC1(Cc2nnc(o2)C(=O)c2nc3ccc(cc3s2)-c2ccccc2)NC(=O)N(CC(F)(F)F)C1=O Show InChI InChI=1S/C23H16F3N5O4S/c1-22(20(33)31(21(34)28-22)11-23(24,25)26)10-16-29-30-18(35-16)17(32)19-27-14-8-7-13(9-15(14)36-19)12-5-3-2-4-6-12/h2-9H,10-11H2,1H3,(H,28,34)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	8.0	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The enzymatic assay was measured using white, opaque 96-well half area plates. Each well contained 60 μL of assay buffer (50 mM HEPES pH 8.0, 50...				US Patent US9169240 (2015) BindingDB Entry DOI: 10.7270/Q2W66JK8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM187291 (US9169240, 31 | US9169240, 38 | US9169240, 40) Show SMILES CC1(Cc2nnc(o2)C(=O)c2nc3ccc(cc3s2)-c2ccccc2)NC(=O)N(CC(F)(F)F)C1=O Show InChI InChI=1S/C23H16F3N5O4S/c1-22(20(33)31(21(34)28-22)11-23(24,25)26)10-16-29-30-18(35-16)17(32)19-27-14-8-7-13(9-15(14)36-19)12-5-3-2-4-6-12/h2-9H,10-11H2,1H3,(H,28,34)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	8.0	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The enzymatic assay was measured using white, opaque 96-well half area plates. Each well contained 60 μL of assay buffer (50 mM HEPES pH 8.0, 50...				US Patent US9169240 (2015) BindingDB Entry DOI: 10.7270/Q2W66JK8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM187291 (US9169240, 31 | US9169240, 38 | US9169240, 40) Show SMILES CC1(Cc2nnc(o2)C(=O)c2nc3ccc(cc3s2)-c2ccccc2)NC(=O)N(CC(F)(F)F)C1=O Show InChI InChI=1S/C23H16F3N5O4S/c1-22(20(33)31(21(34)28-22)11-23(24,25)26)10-16-29-30-18(35-16)17(32)19-27-14-8-7-13(9-15(14)36-19)12-5-3-2-4-6-12/h2-9H,10-11H2,1H3,(H,28,34)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	8.0	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The enzymatic assay was measured using white, opaque 96-well half area plates. Each well contained 60 μL of assay buffer (50 mM HEPES pH 8.0, 50...				US Patent US9169240 (2015) BindingDB Entry DOI: 10.7270/Q2W66JK8
					More data for this Ligand-Target Pair