Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Endothelial lipase' and Ligand = 'BDBM187305'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM187305 (US9169240, 45) Show SMILES CC(C)(C)CN1CCC(CC1)c1nnc(o1)C(=O)c1nc2ccc(cc2s1)-c1ccccc1 Show InChI InChI=1S/C26H28N4O2S/c1-26(2,3)16-30-13-11-18(12-14-30)23-28-29-24(32-23)22(31)25-27-20-10-9-19(15-21(20)33-25)17-7-5-4-6-8-17/h4-10,15,18H,11-14,16H2,1-3H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	8.0	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The enzymatic assay was measured using white, opaque 96-well half area plates. Each well contained 60 μL of assay buffer (50 mM HEPES pH 8.0, 50...				US Patent US9169240 (2015) BindingDB Entry DOI: 10.7270/Q2W66JK8
					More data for this Ligand-Target Pair