Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Endothelial lipase' and Ligand = 'BDBM187340'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM187340 (US9169240, 79) Show SMILES O=C(c1nnc(o1)N1CC[C@H](C1)c1ccccc1)c1nc2ccc(cc2s1)-c1ccccc1 |r| Show InChI InChI=1S/C26H20N4O2S/c31-23(25-27-21-12-11-19(15-22(21)33-25)17-7-3-1-4-8-17)24-28-29-26(32-24)30-14-13-20(16-30)18-9-5-2-6-10-18/h1-12,15,20H,13-14,16H2/t20-/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	310	n/a	n/a	n/a	n/a	8.0	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The enzymatic assay was measured using white, opaque 96-well half area plates. Each well contained 60 μL of assay buffer (50 mM HEPES pH 8.0, 50...				US Patent US9169240 (2015) BindingDB Entry DOI: 10.7270/Q2W66JK8
					More data for this Ligand-Target Pair