Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Endothelial lipase' and Ligand = 'BDBM199225'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Mus musculus (Mouse))	BDBM199225 (US9216998, 8) Show SMILES Nc1cc2CCCn3c(CCCOc4ccccc4)c(c(c1)c23)C(F)(F)F Show InChI InChI=1S/C21H21F3N2O/c22-21(23,24)19-17-13-15(25)12-14-6-4-10-26(20(14)17)18(19)9-5-11-27-16-7-2-1-3-8-16/h1-3,7-8,12-13H,4-6,9-11,25H2	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	7.2	n/a
Janssen Pharmaceutica NV US Patent					Assay Description To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...				US Patent US9216998 (2015) BindingDB Entry DOI: 10.7270/Q22N513F
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM199225 (US9216998, 8) Show SMILES Nc1cc2CCCn3c(CCCOc4ccccc4)c(c(c1)c23)C(F)(F)F Show InChI InChI=1S/C21H21F3N2O/c22-21(23,24)19-17-13-15(25)12-14-6-4-10-26(20(14)17)18(19)9-5-11-27-16-7-2-1-3-8-16/h1-3,7-8,12-13H,4-6,9-11,25H2	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	7.2	n/a
Janssen Pharmaceutica NV US Patent					Assay Description To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...				US Patent US9216998 (2015) BindingDB Entry DOI: 10.7270/Q22N513F
					More data for this Ligand-Target Pair