Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Endothelial lipase' and Ligand = 'BDBM254847'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM254847 (US9493412, 18) Show SMILES CN1CC(C(=O)NCc2ccccc2-c2ccccc2)=C(O)C1=O |t:21| Show InChI InChI=1S/C19H18N2O3/c1-21-12-16(17(22)19(21)24)18(23)20-11-14-9-5-6-10-15(14)13-7-3-2-4-8-13/h2-10,22H,11-12H2,1H3,(H,20,23)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	27	n/a	n/a	n/a	n/a	8.0	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase activity was measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artificial vesicle containing DMPG (Av...				US Patent US9493412 (2016) BindingDB Entry DOI: 10.7270/Q2FX78CV
					More data for this Ligand-Target Pair