Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Endothelial lipase' and Ligand = 'BDBM254871'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM254871 (US9493412, 196) Show SMILES CN1CC(CC1=O)N1CC(C(=O)N[C@H]2CC[C@H](CC2)c2ccccc2)=C(O)C1=O |r,wU:13.13,16.20,t:27,(9.48,.17,;8.14,-.6,;6.68,-.12,;5.78,-1.37,;6.68,-2.61,;8.14,-2.14,;9.48,-2.91,;4.44,-.6,;2.98,-1.07,;2.07,.17,;.53,.17,;-.24,1.51,;-.24,-1.16,;-1.78,-1.16,;-2.55,-2.49,;-4.09,-2.49,;-4.86,-1.16,;-4.09,.17,;-2.55,.17,;-6.4,-1.16,;-7.17,.17,;-8.71,.17,;-9.48,-1.16,;-8.71,-2.49,;-7.17,-2.49,;2.98,1.42,;2.58,2.91,;4.44,.94,;5.78,1.71,)| Show InChI InChI=1S/C22H27N3O4/c1-24-12-17(11-19(24)26)25-13-18(20(27)22(25)29)21(28)23-16-9-7-15(8-10-16)14-5-3-2-4-6-14/h2-6,15-17,27H,7-13H2,1H3,(H,23,28)/t15-,16+,17?	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.25E+3	n/a	n/a	n/a	n/a	8.0	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase activity was measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artificial vesicle containing DMPG (Av...				US Patent US9493412 (2016) BindingDB Entry DOI: 10.7270/Q2FX78CV
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