Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Endothelial lipase' and Ligand = 'BDBM254876'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM254876 (US9493412, 178) Show SMILES CN(CCN1CC(C(=O)N[C@H]2CC[C@H](CC2)c2ccccc2)=C(O)C1=O)C(=O)C=CC(F)(F)F |w:28.30,wU:13.16,10.9,t:23,(8.06,-3.53,;8.06,-1.99,;6.73,-1.22,;5.39,-1.99,;4.06,-1.22,;2.65,-1.84,;1.62,-.7,;.09,-.86,;-.82,.39,;-.54,-2.27,;-2.07,-2.43,;-2.69,-3.84,;-4.23,-4,;-5.13,-2.75,;-4.5,-1.34,;-2.97,-1.18,;-6.66,-2.91,;-7.29,-4.32,;-8.82,-4.48,;-9.73,-3.23,;-9.1,-1.83,;-7.57,-1.67,;2.39,.63,;1.76,2.04,;3.9,.31,;5.04,1.34,;9.39,-1.22,;9.39,.32,;10.73,-1.99,;10.73,-3.53,;12.06,-4.3,;13.39,-5.07,;12.83,-2.96,;11.29,-5.63,)| Show InChI InChI=1S/C24H28F3N3O4/c1-29(20(31)11-12-24(25,26)27)13-14-30-15-19(21(32)23(30)34)22(33)28-18-9-7-17(8-10-18)16-5-3-2-4-6-16/h2-6,11-12,17-18,32H,7-10,13-15H2,1H3,(H,28,33)/b12-11+/t17-,18+	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.92E+3	n/a	n/a	n/a	n/a	8.0	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase activity was measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artificial vesicle containing DMPG (Av...				US Patent US9493412 (2016) BindingDB Entry DOI: 10.7270/Q2FX78CV
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