Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Endothelial lipase' and Ligand = 'BDBM254877'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM254877 (US9493412, 214) Show SMILES CCN1CC(C(=O)NCC2CCc3cnc(-c4ccc(Cl)c(Cl)c4)n3C2)=C(O)C1=O |t:28| Show InChI InChI=1S/C21H22Cl2N4O3/c1-2-26-11-15(18(28)21(26)30)20(29)25-8-12-3-5-14-9-24-19(27(14)10-12)13-4-6-16(22)17(23)7-13/h4,6-7,9,12,28H,2-3,5,8,10-11H2,1H3,(H,25,29)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	460	n/a	n/a	n/a	n/a	8.0	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase activity was measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artificial vesicle containing DMPG (Av...				US Patent US9493412 (2016) BindingDB Entry DOI: 10.7270/Q2FX78CV
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