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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Endothelial lipase' and Ligand = 'BDBM318967'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Endothelial lipase


(Homo sapiens (Human))		BDBM318967
PNG
(US10173991, Example 8 | benzyl N-{4-[2- ({[(cyclop...)
Show SMILES CS(=O)(=O)C(C(=O)NCC(=O)NC1CC1)c1nc2cc(c(F)cc2s1)-c1ccc(NC(=O)OCc2ccccc2)cc1
Show InChI InChI=1S/C29H27FN4O6S2/c1-42(38,39)26(27(36)31-15-25(35)32-19-11-12-19)28-34-23-13-21(22(30)14-24(23)41-28)18-7-9-20(10-8-18)33-29(37)40-16-17-5-3-2-4-6-17/h2-10,13-14,19,26H,11-12,15-16H2,1H3,(H,31,36)(H,32,35)(H,33,37)
KEGG

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem
US Patent
n/an/a 1n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...

US Patent US10173991 (2019)


BindingDB Entry DOI: 10.7270/Q2N018M8
More data for this
Ligand-Target Pair