Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Endothelial lipase' and Ligand = 'BDBM319458'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM319458 (2-(6-{4-[(benzyl- carbamoyl) amino]phenyl}- 5-fluo...) Show SMILES Fc1cc2nc(sc2cc1-c1ccc(NC(=O)NCc2ccccc2)cc1)C(C(=O)NCC(=O)NC1CC1)S(=O)(=O)CCC(F)(F)F Show InChI InChI=1S/C31H29F4N5O5S2/c32-23-15-24-25(14-22(23)19-6-8-21(9-7-19)39-30(43)37-16-18-4-2-1-3-5-18)46-29(40-24)27(47(44,45)13-12-31(33,34)35)28(42)36-17-26(41)38-20-10-11-20/h1-9,14-15,20,27H,10-13,16-17H2,(H,36,42)(H,38,41)(H2,37,39,43)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US10173991 (2019) BindingDB Entry DOI: 10.7270/Q2N018M8
					More data for this Ligand-Target Pair