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Found 1 hit Enz. Inhib. hit(s) with Target = 'Endothelial lipase' and Ligand = 'BDBM319474'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Endothelial lipase


(Homo sapiens (Human))		BDBM319474
PNG
(US10173991, Example 528 | cyclopropylmethyl N-{4-...)
Show SMILES CC(C)S(=O)(=O)C(C(=O)NCC(=O)NC1CC1)c1nc2cc(F)c(cc2s1)-c1ccc(NC(=O)OCC2CC2)cc1
Show InChI InChI=1S/C28H31FN4O6S2/c1-15(2)41(37,38)25(26(35)30-13-24(34)31-18-9-10-18)27-33-22-12-21(29)20(11-23(22)40-27)17-5-7-19(8-6-17)32-28(36)39-14-16-3-4-16/h5-8,11-12,15-16,18,25H,3-4,9-10,13-14H2,1-2H3,(H,30,35)(H,31,34)(H,32,36)
KEGG

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem
US Patent
n/an/a 1n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...

US Patent US10173991 (2019)


BindingDB Entry DOI: 10.7270/Q2N018M8
More data for this
Ligand-Target Pair