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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Endothelin-1 receptor' and Ligand = 'BDBM50105030'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Endothelin-1 receptor


(Sus scrofa)		BDBM50105030
PNG
(CHEMBL177373 | Naphthalene-1-sulfonic acid {6-[2-(...)
Show SMILES Cc1ccc(cc1)-c1c(NS(=O)(=O)c2cccc3ccccc23)ncnc1OCCOc1ncc(Br)cn1
Show InChI InChI=1S/C27H22BrN5O4S/c1-18-9-11-20(12-10-18)24-25(33-38(34,35)23-8-4-6-19-5-2-3-7-22(19)23)31-17-32-26(24)36-13-14-37-27-29-15-21(28)16-30-27/h2-12,15-17H,13-14H2,1H3,(H,31,32,33)
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n/an/a 22n/an/an/an/an/an/a



Tanabe Seiyaku Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibition of [125I]-ET-1 binding to Endothelin A receptor in porcine aortic membrane from endothelial cells

J Med Chem 44: 3355-68 (2001)


BindingDB Entry DOI: 10.7270/Q2QN662B
More data for this
Ligand-Target Pair