BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Endothelin-1 receptor' and Ligand = 'BDBM50329846'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Endothelin-1 receptor (Homo sapiens (Human))	BDBM50329846 (3-(3-Carboxybenzyl)-6-(cyclopropylmethoxy)-1-[(6-e...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	116	n/a	n/a	n/a	n/a	n/a	n/a
St. John's University Curated by ChEMBL					Assay Description Displacement of [125I]ET1 from ETA receptor expressed in african green monkey CCL-81 cells monolayer				Bioorg Med Chem Lett 20: 6840-4 (2010) Article DOI: 10.1016/j.bmcl.2010.08.074 BindingDB Entry DOI: 10.7270/Q2X34XPP
St. John's University Curated by ChEMBL					More data for this Ligand-Target Pair
Endothelin-1 receptor (Homo sapiens (Human))	BDBM50329846 (3-(3-Carboxybenzyl)-6-(cyclopropylmethoxy)-1-[(6-e...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	121	n/a	n/a	n/a	n/a	n/a	n/a
St. John's University Curated by ChEMBL					Assay Description Antagonist activity at ETA receptor (unknown origin) expressed in membranes by radioligand assay				Bioorg Med Chem Lett 27: 2281-2285 (2017) Article DOI: 10.1016/j.bmcl.2017.04.049 BindingDB Entry DOI: 10.7270/Q2Q52S21
St. John's University Curated by ChEMBL					More data for this Ligand-Target Pair