Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ephrin type-B receptor 4' and Ligand = 'BDBM50100323'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50100323 (CHEMBL3321803) Show SMILES COc1ccc(C)c(c1)-n1c(N)c(C(N)=O)c2nc3ccccc3nc12 |(11.88,-35.21,;11.41,-33.74,;9.9,-33.43,;8.86,-34.57,;7.36,-34.25,;6.88,-32.78,;5.37,-32.46,;7.91,-31.64,;9.42,-31.96,;7.44,-30.18,;8.34,-28.94,;9.88,-28.94,;7.44,-27.68,;7.91,-26.22,;9.4,-25.82,;6.88,-25.07,;5.97,-28.16,;4.64,-27.39,;3.3,-28.16,;1.97,-27.39,;.64,-28.16,;.64,-29.7,;1.97,-30.48,;3.3,-29.7,;4.64,-30.48,;5.97,-29.7,)| Show InChI InChI=1S/C19H17N5O2/c1-10-7-8-11(26-2)9-14(10)24-17(20)15(18(21)25)16-19(24)23-13-6-4-3-5-12(13)22-16/h3-9H,20H2,1-2H3,(H2,21,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	720	n/a	n/a	n/a	n/a	n/a	n/a
University of Z£rich Curated by ChEMBL					Assay Description Inhibition of phosphorylation of full-length myc-tagged human EphB4 overexpressed in mouse embryonic fibroblasts after 90 mins by sandwich ELISA				J Med Chem 57: 6834-44 (2014) Article DOI: 10.1021/jm5009242 BindingDB Entry DOI: 10.7270/Q2TQ638D
					More data for this Ligand-Target Pair