Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ephrin type-B receptor 4' and Ligand = 'BDBM50230181'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50230181 (CHEMBL4086694) Show SMILES Nc1n[nH]c2cccc(-c3ccc(NC(=O)C4(CC4)C(=O)Nc4cc(Br)cc(c4)C(F)(F)F)cc3)c12 Show InChI InChI=1S/C25H19BrF3N5O2/c26-15-10-14(25(27,28)29)11-17(12-15)32-23(36)24(8-9-24)22(35)31-16-6-4-13(5-7-16)18-2-1-3-19-20(18)21(30)34-33-19/h1-7,10-12H,8-9H2,(H,31,35)(H,32,36)(H3,30,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.20	n/a	n/a	n/a	n/a	n/a	n/a
Xi'an Jiaotong University Curated by ChEMBL					Assay Description Inhibition of EphB4 (unknown origin) after 60 mins by ADP-Glo assay				Eur J Med Chem 127: 275-285 (2017) Article DOI: 10.1016/j.ejmech.2016.12.059 BindingDB Entry DOI: 10.7270/Q2XW4N27
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