Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ephrin type-B receptor 4' and Ligand = 'BDBM50283033'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50283033 (CHEMBL4160854) Show SMILES Nc1n[nH]c2cccc(-c3ccc(NC(=S)Nc4cc(Br)ccc4OC(F)(F)F)cc3)c12 Show InChI InChI=1S/C21H15BrF3N5OS/c22-12-6-9-17(31-21(23,24)25)16(10-12)28-20(32)27-13-7-4-11(5-8-13)14-2-1-3-15-18(14)19(26)30-29-15/h1-10H,(H3,26,29,30)(H2,27,28,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.70	n/a	n/a	n/a	n/a	n/a	n/a
Xi'an Jiaotong University Curated by ChEMBL					Assay Description Inhibition of EPHB4 (unknown origin) after 4 hrs by ADP-Glo assay				Eur J Med Chem 141: 373-385 (2017) Article DOI: 10.1016/j.ejmech.2017.10.008 BindingDB Entry DOI: 10.7270/Q29889J3
					More data for this Ligand-Target Pair