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Found 1 hit Enz. Inhib. hit(s) with Target = 'Epidermal/Hepatocyte growth factor receptor' and Ligand = 'BDBM24470'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Epidermal/Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM24470
PNG
(7-methoxy-4-({6-phenyl-[1,2,4]triazolo[4,3-a]pyrid...)
Show SMILES COc1ccc2c(OCc3nnc4ccc(nn34)-c3ccccc3)ccnc2c1
Show InChI InChI=1S/C22H17N5O2/c1-28-16-7-8-17-19(13-16)23-12-11-20(17)29-14-22-25-24-21-10-9-18(26-27(21)22)15-5-3-2-4-6-15/h2-13H,14H2,1H3
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PDB
Article
PubMed
n/an/a 90n/an/an/an/an/an/a



China Pharmaceutical University



Assay Description
The c-Met kinase activity as tested with enzyme-linked immunosorbent assays (ELISAs) as previously reported protocol [Qiang et al., Bioorg. Med. Chem...


Bioorg Chem 70: 126-132 (2017)


Article DOI: 10.1016/j.bioorg.2016.12.002
BindingDB Entry DOI: 10.7270/Q23X85HP
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)