Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM133697'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM133697 (US8846699, 13) Show SMILES CC(=O)NCCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C Show InChI InChI=1S/C22H21BrFN5O3/c1-3-21(31)28-19-10-15-18(11-20(19)32-8-4-7-25-13(2)30)26-12-27-22(15)29-17-6-5-14(23)9-16(17)24/h3,5-6,9-12H,1,4,7-8H2,2H3,(H,25,30)(H,28,31)(H,26,27,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	7.4	25
Hanmi Pharm. Co., Ltd. US Patent					Assay Description EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...				US Patent US8846699 (2014) BindingDB Entry DOI: 10.7270/Q2KW5DRK
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