Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM3663'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM3663 (4-N-(3-bromophenyl)-7-N-[3-(4-methylpiperazin-1-yl...) Show SMILES CN1CCN(CCCNc2cc3ncnc(Nc4cccc(Br)c4)c3cn2)CC1 Show InChI InChI=1S/C21H26BrN7/c1-28-8-10-29(11-9-28)7-3-6-23-20-13-19-18(14-24-20)21(26-15-25-19)27-17-5-2-4-16(22)12-17/h2,4-5,12-15H,3,6-11H2,1H3,(H,23,24)(H,25,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 40: 3915-25 (1997) Article DOI: 10.1021/jm970366v BindingDB Entry DOI: 10.7270/Q2NS0S2V
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