Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM368394'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM368394 (US10227342, Example 28) Show SMILES COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OCC(C)C)c(n1)-c1cn(C)c2ccccc12 Show InChI InChI=1S/C33H41N7O4/c1-9-30(41)35-25-16-26(29(43-8)17-28(25)39(6)15-14-38(4)5)36-33-34-18-23(32(42)44-20-21(2)3)31(37-33)24-19-40(7)27-13-11-10-12-22(24)27/h9-13,16-19,21H,1,14-15,20H2,2-8H3,(H,35,41)(H,34,36,37)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Neuroscience					Assay Description A compound's ability in selectively inhibiting EGFR exon 20 insertion mutations can be assessed using Ba/F3 cells, a murine pro-B cell line, whic...				J Med Chem 51: 1730-9 (2008) BindingDB Entry DOI: 10.7270/Q21Z46Q0
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM368394 (US10227342, Example 28) Show SMILES COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OCC(C)C)c(n1)-c1cn(C)c2ccccc12 Show InChI InChI=1S/C33H41N7O4/c1-9-30(41)35-25-16-26(29(43-8)17-28(25)39(6)15-14-38(4)5)36-33-34-18-23(32(42)44-20-21(2)3)31(37-33)24-19-40(7)27-13-11-10-12-22(24)27/h9-13,16-19,21H,1,14-15,20H2,2-8H3,(H,35,41)(H,34,36,37)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Neuroscience					Assay Description A compound's ability in selectively inhibiting EGFR exon 20 insertion mutations can be assessed using Ba/F3 cells, a murine pro-B cell line, whic...				J Med Chem 51: 1730-9 (2008) BindingDB Entry DOI: 10.7270/Q21Z46Q0
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM368394 (US10227342, Example 28) Show SMILES COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OCC(C)C)c(n1)-c1cn(C)c2ccccc12 Show InChI InChI=1S/C33H41N7O4/c1-9-30(41)35-25-16-26(29(43-8)17-28(25)39(6)15-14-38(4)5)36-33-34-18-23(32(42)44-20-21(2)3)31(37-33)24-19-40(7)27-13-11-10-12-22(24)27/h9-13,16-19,21H,1,14-15,20H2,2-8H3,(H,35,41)(H,34,36,37)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	142	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM368394 (US10227342, Example 28) Show SMILES COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C(=O)OCC(C)C)c(n1)-c1cn(C)c2ccccc12 Show InChI InChI=1S/C33H41N7O4/c1-9-30(41)35-25-16-26(29(43-8)17-28(25)39(6)15-14-38(4)5)36-33-34-18-23(32(42)44-20-21(2)3)31(37-33)24-19-40(7)27-13-11-10-12-22(24)27/h9-13,16-19,21H,1,14-15,20H2,2-8H3,(H,35,41)(H,34,36,37)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Neuroscience					Assay Description A compound's ability in selectively inhibiting Her2 exon 20 YVMA insertion mutations can be assessed using Ba/F3 cells, a murine pro-B cell line,...				J Med Chem 51: 1730-9 (2008) BindingDB Entry DOI: 10.7270/Q21Z46Q0
					More data for this Ligand-Target Pair