Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM4019'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM4019 (4-methoxy-2-{[4-methoxy-1-methyl-3-(phenylcarbamoy...) Show SMILES COc1cccc2n(C)c(SSc3c(C(=O)Nc4ccccc4)c4c(OC)cccc4n3C)c(C(=O)Nc3ccccc3)c12 Show InChI InChI=1S/C34H30N4O4S2/c1-37-23-17-11-19-25(41-3)27(23)29(31(39)35-21-13-7-5-8-14-21)33(37)43-44-34-30(32(40)36-22-15-9-6-10-16-22)28-24(38(34)2)18-12-20-26(28)42-4/h5-20H,1-4H3,(H,35,39)(H,36,40)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	7.4	22
University of Auckland					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 37: 2033-42 (1994) Article DOI: 10.1021/jm00039a016 BindingDB Entry DOI: 10.7270/Q2H41PMC
					More data for this Ligand-Target Pair