Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM4280'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM4280 (2-(1H-pyrazol-5-ylmethylidene)propanedinitrile | T...) Show SMILES N#CC(=Cc1ccn[nH]1)C#N |(14.9,-11.28,;14.93,-9.6,;14.95,-7.91,;13.61,-7.16,;12.2,-7.71,;11.72,-6.24,;10.18,-6.24,;9.7,-7.71,;10.95,-8.61,;16.28,-7.12,;17.6,-6.34,)| Show InChI InChI=1S/C7H4N4/c8-4-6(5-9)3-7-1-2-10-11-7/h1-3H,(H,10,11)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.48E+6	n/a	n/a	n/a	n/a	7.6	22
Hebrew University of Jerusalem					Assay Description The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.				J Med Chem 34: 1896-907 (1991) Article DOI: 10.1021/jm00110a022 BindingDB Entry DOI: 10.7270/Q2KW5D7V
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