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Found 1 hit Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50102087'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50102087
PNG
((6-{2-[Bis-(2-methoxy-ethyl)-amino]-ethoxy}-7-meth...)
Show SMILES COCCN(CCOC)CCOc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OC
Show InChI InChI=1S/C23H28ClFN4O4/c1-30-9-6-29(7-10-31-2)8-11-33-22-13-17-20(14-21(22)32-3)26-15-27-23(17)28-16-4-5-19(25)18(24)12-16/h4-5,12-15H,6-11H2,1-3H3,(H,26,27,28)
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PubMed
n/an/a 61n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Epidermal growth factor receptor (EGFR-TK) from A431 vulval squamous carcinoma cells using TKI assay

Bioorg Med Chem Lett 11: 1911-4 (2001)


BindingDB Entry DOI: 10.7270/Q2XD1261
More data for this
Ligand-Target Pair