Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50142035'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50142035 (CHEMBL3759696) Show SMILES CC1(C)OCc2c1nc(nc2Nc1n[nH]c2ccccc12)-c1c[nH]nn1 Show InChI InChI=1S/C17H16N8O/c1-17(2)13-10(8-26-17)14(21-16(19-13)12-7-18-25-23-12)20-15-9-5-3-4-6-11(9)22-24-15/h3-7H,8H2,1-2H3,(H,18,23,25)(H2,19,20,21,22,24)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	732	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of EGFR T790M/L858R mutant (unknown origin)				Bioorg Med Chem Lett 26: 534-9 (2016) Article DOI: 10.1016/j.bmcl.2015.11.078 BindingDB Entry DOI: 10.7270/Q2HH6MZQ
					More data for this Ligand-Target Pair