BindingDB PrimarySearch

Found 3 hits Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50171908'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50171908 (CHEMBL3805238 \| US10106508, Compound I-38) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.70	n/a	n/a	n/a	n/a	n/a	n/a
Beijing University of Technology Curated by ChEMBL					Assay Description Inhibition of wild type EGFR (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 hr by kinase-glo...				Bioorg Med Chem 24: 2871-2881 (2016) Article DOI: 10.1016/j.bmc.2016.01.003 BindingDB Entry DOI: 10.7270/Q2NP269P
Beijing University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50171908 (CHEMBL3805238 \| US10106508, Compound I-38) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
BEIJING SCITECH-MQ PHARMACEUTICALS LIMITED US Patent					Assay Description The sample compounds were dissolved in DMSO and diluted it to 500 μM concentration with DMSO and transferred to a dose plate. The compounds were...				US Patent US10106508 (2018) BindingDB Entry DOI: 10.7270/Q26M38VB
BEIJING SCITECH-MQ PHARMACEUTICALS LIMITED US Patent					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50171908 (CHEMBL3805238 \| US10106508, Compound I-38) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
Beijing University of Technology Curated by ChEMBL					Assay Description Inhibition of EGFR T790M/L858R double mutant (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 ...				Bioorg Med Chem 24: 2871-2881 (2016) Article DOI: 10.1016/j.bmc.2016.01.003 BindingDB Entry DOI: 10.7270/Q2NP269P
Beijing University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair