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Found 1 hit Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50190726'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50190726
PNG
(CHEMBL3969628)
Show SMILES Clc1cc(Nc2ncnc3cc4oc(=O)n(CCOC(=O)CBr)c4cc23)ccc1N1CCCCC1
Show InChI InChI=1S/C24H23BrClN5O4/c25-13-22(32)34-9-8-31-20-11-16-18(12-21(20)35-24(31)33)27-14-28-23(16)29-15-4-5-19(17(26)10-15)30-6-2-1-3-7-30/h4-5,10-12,14H,1-3,6-9,13H2,(H,27,28,29)
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PC cid
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Similars
Article
PubMed
n/an/a 184n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of GST-tagged wild type recombinant human EGFR (668 to 1210 residues) expressed in baculovirus after 1 hr by Z-lyte assay

Eur J Med Chem 120: 26-36 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.072
BindingDB Entry DOI: 10.7270/Q20C4XP2
More data for this
Ligand-Target Pair