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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50230562'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50230562
PNG
(CHEMBL4079768)
Show SMILES NP(=O)(OCCCOc1ccc2ncnc(Nc3cccc(c3)C#C)c2c1)N(CCCl)CCCl
Show InChI InChI=1S/C23H26Cl2N5O3P/c1-2-18-5-3-6-19(15-18)29-23-21-16-20(7-8-22(21)27-17-28-23)32-13-4-14-33-34(26,31)30(11-9-24)12-10-25/h1,3,5-8,15-17H,4,9-14H2,(H2,26,31)(H,27,28,29)
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Article
PubMed
n/an/a 7.20n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human GST-tagged EGFR cytoplasmic domain (668 to 1210 residues) expressed in baculovirus expression system using Poly (Glu,...

Eur J Med Chem 127: 442-458 (2017)


Article DOI: 10.1016/j.ejmech.2016.12.055
BindingDB Entry DOI: 10.7270/Q2S46V7W
More data for this
Ligand-Target Pair