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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50230569'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50230569
PNG
(CHEMBL4087646)
Show SMILES NP(=O)(OCCCCOc1ccc2ncnc(Nc3ccc(F)c(Cl)c3)c2c1)N(CCCl)CCCl
Show InChI InChI=1S/C22H26Cl3FN5O3P/c23-7-9-31(10-8-24)35(27,32)34-12-2-1-11-33-17-4-6-21-18(14-17)22(29-15-28-21)30-16-3-5-20(26)19(25)13-16/h3-6,13-15H,1-2,7-12H2,(H2,27,32)(H,28,29,30)
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KEGG

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PC cid
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Similars
Article
PubMed
n/an/a 6n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human GST-tagged EGFR cytoplasmic domain (668 to 1210 residues) expressed in baculovirus expression system using Poly (Glu,...

Eur J Med Chem 127: 442-458 (2017)


Article DOI: 10.1016/j.ejmech.2016.12.055
BindingDB Entry DOI: 10.7270/Q2S46V7W
More data for this
Ligand-Target Pair