Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50234176'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50234176 (CHEMBL4087740) Show SMILES COc1cc(ccc1Nc1ncc2c(C)cc(=O)n(-c3cc(F)cc(NC(=O)C=C)c3)c2n1)N1CCN(C)CC1 Show InChI InChI=1S/C29H30FN7O3/c1-5-26(38)32-20-13-19(30)14-22(15-20)37-27(39)12-18(2)23-17-31-29(34-28(23)37)33-24-7-6-21(16-25(24)40-4)36-10-8-35(3)9-11-36/h5-7,12-17H,1,8-11H2,2-4H3,(H,32,38)(H,31,33,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Guangzhou Institutes of Biomedicine and Health Curated by ChEMBL					Assay Description Inhibition of N-terminal 6His/TEV protease cleavage site-tagged wild type human EGFR using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISA				Eur J Med Chem 126: 1107-1117 (2017) Article DOI: 10.1016/j.ejmech.2016.12.006 BindingDB Entry DOI: 10.7270/Q2F47RD5
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