Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50234180'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50234180 (CHEMBL4103194) Show SMILES COc1cc(ccc1Nc1ncc2c(C)cc(=O)n(-c3cc(NC(=O)C=C)cc(c3)C(F)(F)F)c2n1)N1CCN(C)C(C)C1 Show InChI InChI=1S/C31H32F3N7O3/c1-6-27(42)36-21-12-20(31(32,33)34)13-23(14-21)41-28(43)11-18(2)24-16-35-30(38-29(24)41)37-25-8-7-22(15-26(25)44-5)40-10-9-39(4)19(3)17-40/h6-8,11-16,19H,1,9-10,17H2,2-5H3,(H,36,42)(H,35,37,38)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
Guangzhou Institutes of Biomedicine and Health Curated by ChEMBL					Assay Description Inhibition of N-terminal 6His/TEV protease cleavage site-tagged wild type human EGFR using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISA				Eur J Med Chem 126: 1107-1117 (2017) Article DOI: 10.1016/j.ejmech.2016.12.006 BindingDB Entry DOI: 10.7270/Q2F47RD5
					More data for this Ligand-Target Pair