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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50234196'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50234196
PNG
(CHEMBL4101484)
Show SMILES COc1cc(ccc1Nc1ncc2c(C)cc(=O)n(C3CCN(CC3)C(=O)C=C)c2n1)N1CCN(C)CC1
Show InChI InChI=1S/C28H35N7O3/c1-5-25(36)34-10-8-20(9-11-34)35-26(37)16-19(2)22-18-29-28(31-27(22)35)30-23-7-6-21(17-24(23)38-4)33-14-12-32(3)13-15-33/h5-7,16-18,20H,1,8-15H2,2-4H3,(H,29,30,31)
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Similars
Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Guangzhou Institutes of Biomedicine and Health

Curated by ChEMBL


Assay Description
Inhibition of N-terminal 6His/TEV protease cleavage site-tagged wild type human EGFR using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISA

Eur J Med Chem 126: 1107-1117 (2017)


Article DOI: 10.1016/j.ejmech.2016.12.006
BindingDB Entry DOI: 10.7270/Q2F47RD5
More data for this
Ligand-Target Pair